Protein Engineering

Using engineered enzymes for tailoring the production of fatty acids and oils in transgenic crops is a major emphasis of agricultural biotechnology, but requires significant knowledge of the structure-function relationships in the enzyme target for successful redesign. Fortunately, the three-dimensional architecture and detailed chemical reaction mechanism of condensing enzymes in plants are well studied. This detailed understanding of how condensing enzymes function provides a foundation for experiments aimed at altering their chemistry. This work sets a precedent for engineering not only the condensing enzymes but other proteins involved in fatty acid and oil synthesis in plants.

• Supplemental Notes:
  • Program Information: Advanced Research, Biobased Research

Language

• English

Project

• Status: Active
• Sponsor Organizations:

  Research and Innovative Technology Administration

  Office of Research, Development, and Technology
  1200 New Jersey Avenue, SE
  Washington, DC    20590
• Project Managers:

  Johnson, Shawn

• Start Date: 20120510
• Expected Completion Date: 0
• Actual Completion Date: 0
• Source Data: RiP Project 31304

Subject/Index Terms

• TRT Terms: Chemical reactions; Crops; Oils; Plants; Technology
• Uncontrolled Terms: Enzymes; Fatty acids
• Subject Areas: Materials; Transportation (General); I15: Environment;

Filing Info

• Accession Number: 01467598
• Record Type: Research project
• Source Agency: Department of Transportation
• Files: RiP, USDOT
• Created Date: Jan 3 2013 3:35PM