Protein Engineering

Using engineered enzymes for tailoring the production of fatty acids and oils in transgenic crops is a major emphasis of agricultural biotechnology, but requires significant knowledge of the structure-function relationships in the enzyme target for successful redesign. Fortunately, the three-dimensional architecture and detailed chemical reaction mechanism of condensing enzymes in plants are well studied. This detailed understanding of how condensing enzymes function provides a foundation for experiments aimed at altering their chemistry. This work sets a precedent for engineering not only the condensing enzymes but other proteins involved in fatty acid and oil synthesis in plants.

  • Supplemental Notes:
    • Program Information: Advanced Research, Biobased Research


  • English


  • Status: Active
  • Sponsor Organizations:

    Research and Innovative Technology Administration

    Office of Research, Development, and Technology
    1200 New Jersey Avenue, SE
    Washington, DC    20590
  • Project Managers:

    Johnson, Shawn

  • Start Date: 20120510
  • Expected Completion Date: 0
  • Actual Completion Date: 0
  • Source Data: RiP Project 31304

Subject/Index Terms

Filing Info

  • Accession Number: 01467598
  • Record Type: Research project
  • Source Agency: Department of Transportation
  • Files: RIP, USDOT
  • Created Date: Jan 3 2013 3:35PM