Protein Engineering
Using engineered enzymes for tailoring the production of fatty acids and oils in transgenic crops is a major emphasis of agricultural biotechnology, but requires significant knowledge of the structure-function relationships in the enzyme target for successful redesign. Fortunately, the three-dimensional architecture and detailed chemical reaction mechanism of condensing enzymes in plants are well studied. This detailed understanding of how condensing enzymes function provides a foundation for experiments aimed at altering their chemistry. This work sets a precedent for engineering not only the condensing enzymes but other proteins involved in fatty acid and oil synthesis in plants.
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Supplemental Notes:
- Program Information: Advanced Research, Biobased Research
Language
- English
Project
- Status: Active
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Sponsor Organizations:
Research and Innovative Technology Administration
Office of Research, Development, and Technology
1200 New Jersey Avenue, SE
Washington, DC 20590 -
Project Managers:
Johnson, Shawn
- Start Date: 20120510
- Expected Completion Date: 0
- Actual Completion Date: 0
- Source Data: RiP Project 31304
Subject/Index Terms
- TRT Terms: Chemical reactions; Crops; Oils; Plants; Technology
- Uncontrolled Terms: Enzymes; Fatty acids
- Subject Areas: Materials; Transportation (General); I15: Environment;
Filing Info
- Accession Number: 01467598
- Record Type: Research project
- Source Agency: Department of Transportation
- Files: RIP, USDOT
- Created Date: Jan 3 2013 3:35PM